You can watch Dr. Klotman’s Week 310 video address here. My summary and comments follow.

Vaccines

  • Researchers are exploring “broad spectrum” vaccines in mice models. The idea is to activate the immune system using some “alarm bell” molecules (encased in a liposome) that modulate the immune response.
  • The effect of this “liposomal vaccine” was to shorten the time that the immune system takes to respond to a new foreign antigen – virus, bacteria, or allergen.
  • Recent studies show no link between maternal vaccination for COVID and autism among their children.
  • Meningococcal meningitis cases have been increasing in the US since 2021, and yet the CDC has removed the recommendation for vaccination for young people.
  • Rotavirus and RSV vaccines for kids are no longer recommended by the CDC. Expect to see more preventable pediatric deaths from both diseases.
  • The CDC no longer recommends Hepatitis B vaccine for infants. Expect to see more cases of vaccine-preventable childhood cirrhosis and hepatoma (liver cancer).

My Comment: The mouse model strategy isn’t so much a vaccine as it is an immune system primer of sorts. Until this work in mice, most immune modulation strategies have focused on down-regulating rather than stimulating immune – e.g. suppressing autoimmune responses. The other thought is how long it will take RFK and his minions to defund this kind of research. The new CDC childhood vaccination schedule is a travesty of quack science.

Measles

  • Spread of the virus continues. If goes on for 12+ months without abating, the US, like Canada, will lose its designation as a Measles-free country.
  • So far, we have had 972 cases this year. 94% were unvaccinated; 3% had had only one of the two recommended doses of MMR vaccine. This is the same pattern we saw in 2025. Vaccination works!
  • 38 cases have required hospitalization.
  • South Carolina and Utah are the current Measles hot spots. Florida is #3.
  • There are >15 cases in at least five other states, and sporadic cases in another 20.

Political Crap

  • The NIAID (government agency focused on Infectious Diseases) had sent out a directive to scrub government web sites of references to Biodefense and Pandemic Preparedness.
  • The message heralds a defunding of projects that would prepare the US for another COVID or similar deadly pandemic.

My Comment: We saw how well this strategy worked during the first Trump term. It was such a rush; let’s do it again! Who needs a stockpile of ventilators and personal protective equipment? We can afford a few million preventable deaths. We can always make more people, right?

TEPHI curves

  • As respiratory virus season draws to a close, wastewater virus levels are falling for most diseases except RSV and Human metapneumovirus.
  • COVID levels remain low.
  • Influenza cases are falling, but Influenza is still spreading.

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